Statin-induced inhibition of MCF-7 breast cancer cell proliferation is related to cell cycle arrest and apoptotic and necrotic cell death mediated by an enhanced oxidative stress. [electronic resource]
Producer: 20080814Description: 698-707 p. digitalISSN:- 1532-4192
- Acetylcysteine -- pharmacology
- Antineoplastic Agents -- pharmacology
- Antioxidants -- pharmacology
- Apoptosis -- drug effects
- Atorvastatin
- Breast Neoplasms -- metabolism
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Membrane -- drug effects
- Cell Proliferation -- drug effects
- DNA Replication -- drug effects
- Dose-Response Relationship, Drug
- Fatty Acids, Monounsaturated -- pharmacology
- Female
- Fluvastatin
- Heptanoic Acids -- pharmacology
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Indoles -- pharmacology
- Membrane Potential, Mitochondrial -- drug effects
- Necrosis
- Oxidative Stress -- drug effects
- Pyrroles -- pharmacology
- Reactive Oxygen Species -- metabolism
- Simvastatin -- pharmacology
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Publication Type: Journal Article
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