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Aminodifluorosulfinium salts: selective fluorination reagents with enhanced thermal stability and ease of handling. [electronic resource] by
- L'heureux, Alexandre
- Beaulieu, Francis
- Bennett, Christopher
- Bill, David R
- Clayton, Simon
- Laflamme, François
- Mirmehrabi, Mahmoud
- Tadayon, Sam
- Tovell, David
- Couturier, Michel
Producer: 20100901
In:
The Journal of organic chemistry vol. 75
Availability: No items available.
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New azole antagonists with high affinity for the P2Y(1) receptor. [electronic resource] by
- Ruel, Réjean
- L'Heureux, Alexandre
- Thibeault, Carl
- Daris, Jean-Paul
- Martel, Alain
- Price, Laura A
- Wu, Qimin
- Hua, Ji
- Wexler, Ruth R
- Rehfuss, Robert
- Lam, Patrick Y S
Producer: 20140424
In:
Bioorganic & medicinal chemistry letters vol. 23
Availability: No items available.
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Synthesis and structure-activity relationship of acrylamides as KCNQ2 potassium channel openers. [electronic resource] by
- Wu, Yong-Jin
- He, Huan
- Sun, Li-Qiang
- L'Heureux, Alexandre
- Chen, Jie
- Dextraze, Pierre
- Starrett, John E
- Boissard, Christopher G
- Gribkoff, Valentin K
- Natale, Joanne
- Dworetzky, Steven I
Producer: 20040702
In:
Journal of medicinal chemistry vol. 47
Availability: No items available.
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(S,E)-N-[1-(3-heteroarylphenyl)ethyl]-3-(2-fluorophenyl)acrylamides: synthesis and KCNQ2 potassium channel opener activity. [electronic resource] by
- L'Heureux, Alexandre
- Martel, Alain
- He, Huan
- Chen, Jie
- Sun, Li-Qiang
- Starrett, John E
- Natale, Joanne
- Dworetzky, Steven I
- Knox, Ronald J
- Harden, David G
- Weaver, David
- Thompson, Mark W
- Wu, Yong-Jin
Producer: 20050628
In:
Bioorganic & medicinal chemistry letters vol. 15
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Potent P2Y1 urea antagonists bearing various cyclic amine scaffolds. [electronic resource] by
- Ruel, Réjean
- L'Heureux, Alexandre
- Thibeault, Carl
- Lapointe, Philippe
- Martel, Alain
- Qiao, Jennifer X
- Hua, Ji
- Price, Laura A
- Wu, Qimin
- Chang, Ming
- Zheng, Joanna
- Huang, Christine S
- Wexler, Ruth R
- Rehfuss, Robert
- Lam, Patrick Y S
Producer: 20140725
In:
Bioorganic & medicinal chemistry letters vol. 23
Availability: No items available.
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Discovery and preclinical studies of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737), an in vivo active potent VEGFR-2 inhibitor. [electronic resource] by
- Ruel, Réjean
- Thibeault, Carl
- L'Heureux, Alexandre
- Martel, Alain
- Cai, Zhen-Wei
- Wei, Donna
- Qian, Ligang
- Barrish, Joel C
- Mathur, Arvind
- D'Arienzo, Celia
- Hunt, John T
- Kamath, Amrita
- Marathe, Punit
- Zhang, Yueping
- Derbin, George
- Wautlet, Barri
- Mortillo, Steven
- Jeyaseelan, Robert
- Henley, Benjamin
- Tejwani, Ravindra
- Bhide, Rajeev S
- Trainor, George L
- Fargnoli, Joseph
- Lombardo, Louis J
Producer: 20080715
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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10.
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(S)-N-[1-(3-morpholin-4-ylphenyl)ethyl]- 3-phenylacrylamide: an orally bioavailable KCNQ2 opener with significant activity in a cortical spreading depression model of migraine. [electronic resource] by
- Wu, Yong-Jin
- Boissard, Christopher G
- Greco, Corinne
- Gribkoff, Valentin K
- Harden, David G
- He, Huan
- L'Heureux, Alexandre
- Kang, Shing Hong
- Kinney, Gene G
- Knox, Ronald J
- Natale, Joanne
- Newton, Amy E
- Lehtinen-Oboma, Sanna
- Sinz, Michael W
- Sivarao, Digavalli V
- Starrett, John E
- Sun, Li-Qiang
- Tertyshnikova, Svetlana
- Thompson, Mark W
- Weaver, David
- Wong, Henry S
- Zhang, Lei
- Dworetzky, Steven I
Producer: 20030818
In:
Journal of medicinal chemistry vol. 46
Availability: No items available.
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11.
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Conformationally constrained ortho-anilino diaryl ureas: discovery of 1-(2-(1'-neopentylspiro[indoline-3,4'-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea, a potent, selective, and bioavailable P2Y1 antagonist. [electronic resource] by
- Qiao, Jennifer X
- Wang, Tammy C
- Ruel, Réjean
- Thibeault, Carl
- L'Heureux, Alexandre
- Schumacher, William A
- Spronk, Steven A
- Hiebert, Sheldon
- Bouthillier, Gilles
- Lloyd, John
- Pi, Zulan
- Schnur, Dora M
- Abell, Lynn M
- Hua, Ji
- Price, Laura A
- Liu, Eddie
- Wu, Qimin
- Steinbacher, Thomas E
- Bostwick, Jeffrey S
- Chang, Ming
- Zheng, Joanna
- Gao, Qi
- Ma, Baoqing
- McDonnell, Patricia A
- Huang, Christine S
- Rehfuss, Robert
- Wexler, Ruth R
- Lam, Patrick Y S
Producer: 20140130
In:
Journal of medicinal chemistry vol. 56
Availability: No items available.
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