A 150-base pair 5' region of the MHC class I HLA-B7 gene is sufficient to direct tissue-specific expression and locus control region activity: the alpha site determines efficient expression and in vivo occupancy at multiple cis-active sites throughout this region. [electronic resource]
Producer: 19971125Description: 4913-29 p. digitalISSN:- 0022-1767
- Animals
- Base Composition
- Base Sequence
- Binding Sites -- genetics
- Conserved Sequence -- immunology
- Embryo, Mammalian
- Embryonic Development -- immunology
- Female
- Gene Expression Regulation -- immunology
- Genes, MHC Class I
- HLA-B7 Antigen -- genetics
- Humans
- Mice
- Mice, Transgenic
- Molecular Sequence Data
- Organ Specificity -- genetics
- Pregnancy
- Transgenes -- immunology
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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