γ-Hydroxyethyl piperidine iminosugar and N-alkylated derivatives: a study of their activity as glycosidase inhibitors and as immunosuppressive agents. [electronic resource]
Producer: 20150722Description: 5776-82 p. digitalISSN:- 1464-3391
- Alkylation
- Binding Sites
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cells, Cultured
- Enzyme Inhibitors -- chemical synthesis
- Humans
- Imino Sugars -- chemical synthesis
- Immunosuppressive Agents -- chemical synthesis
- Jurkat Cells
- Leukocytes, Mononuclear -- cytology
- Molecular Docking Simulation
- Piperidines -- chemistry
- Protein Structure, Tertiary
- alpha-Galactosidase -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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