Estrogen receptor potentiates mTORC2 signaling in breast cancer cells by upregulating superoxide anions. [electronic resource]
Producer: 20130610Description: 1929-41 p. digitalISSN:- 1873-4596
- Breast Neoplasms -- metabolism
- Cell Line, Tumor
- Disease Progression
- Estradiol -- pharmacology
- Female
- Humans
- MCF-7 Cells
- Mechanistic Target of Rapamycin Complex 2
- Mitochondria -- metabolism
- Multiprotein Complexes -- metabolism
- Oxidation-Reduction
- RNA Interference
- RNA, Small Interfering
- Reactive Oxygen Species -- metabolism
- Receptors, Estrogen -- metabolism
- Signal Transduction -- physiology
- Superoxide Dismutase -- genetics
- Superoxides -- metabolism
- TOR Serine-Threonine Kinases -- metabolism
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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