Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress. [electronic resource]
Producer: 20161107Description: 86 p. digitalISSN:- 1479-5876
- Aging -- pathology
- Animals
- Antioxidants -- metabolism
- Autophagy
- Down-Regulation -- genetics
- Fluorescent Antibody Technique
- Gene Deletion
- Glutathione -- metabolism
- Heart Atria -- metabolism
- Hypertrophy
- Lipid Peroxidation
- Mice, Inbred C57BL
- Models, Biological
- NF-E2-Related Factor 2 -- deficiency
- Oxidative Stress
- Physical Conditioning, Animal
- Reactive Oxygen Species -- metabolism
- Signal Transduction
- Stress, Physiological
- Transcription, Genetic
- Ubiquitinated Proteins -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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