Pannexin-2-deficiency sensitizes pancreatic β-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo. [electronic resource]
Producer: 20171121Description: 108-121 p. digitalISSN:- 1872-8057
- Animals
- Apoptosis -- drug effects
- Connexins -- deficiency
- Cytokines -- pharmacology
- Gene Knockdown Techniques
- Glucose Intolerance -- metabolism
- Humans
- Hyperglycemia -- pathology
- Inflammation -- pathology
- Insulin-Secreting Cells -- metabolism
- Mice, Inbred C57BL
- Nitric Oxide Synthase Type II -- metabolism
- Phosphorylation -- drug effects
- Rats
- STAT3 Transcription Factor -- metabolism
- Streptozocin
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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