The BET bromodomain inhibitor JQ1 suppresses growth of pancreatic ductal adenocarcinoma in patient-derived xenograft models. [electronic resource]
Producer: 20160718Description: 833-45 p. digitalISSN:- 1476-5594
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Azepines -- pharmacology
- Carcinoma, Pancreatic Ductal -- pathology
- Gene Expression -- drug effects
- Genes, myc
- Humans
- Immunoblotting
- Immunohistochemistry
- Mice
- Mice, SCID
- Nerve Tissue Proteins -- antagonists & inhibitors
- Oligonucleotide Array Sequence Analysis
- Pancreatic Neoplasms -- pathology
- Polymerase Chain Reaction
- Receptors, Cell Surface -- antagonists & inhibitors
- Triazoles -- pharmacology
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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