Down-regulation of HLA Class I and NKG2D ligands through a concerted action of MAPK and DNA methyltransferases in colorectal cancer cells. [electronic resource]
Producer: 20090828Description: 1626-39 p. digitalISSN:- 1097-0215
- Antineoplastic Agents -- pharmacology
- Benzenesulfonates -- pharmacology
- Butadienes -- pharmacology
- Colonic Neoplasms -- genetics
- DNA (Cytosine-5-)-Methyltransferase 1
- DNA (Cytosine-5-)-Methyltransferases -- metabolism
- Down-Regulation
- Enzyme Inhibitors -- pharmacology
- GPI-Linked Proteins
- Gene Expression Regulation, Neoplastic
- HCT116 Cells
- HLA-A2 Antigen -- metabolism
- Humans
- Intercellular Signaling Peptides and Proteins -- metabolism
- Killer Cells, Natural -- immunology
- Mitogen-Activated Protein Kinase Kinases -- metabolism
- Mutation
- Niacinamide -- analogs & derivatives
- Nitriles -- pharmacology
- Phenylurea Compounds
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins p21(ras)
- Pyridines -- pharmacology
- Sorafenib
- ras Proteins -- metabolism
- DNA Methyltransferase 3B
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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