Achieving signalling selectivity of ligands for the corticotropin-releasing factor type 1 receptor by modifying the agonist's signalling domain. [electronic resource]
Producer: 20071102Description: 851-9 p. digitalISSN:- 0007-1188
- Amphibian Proteins
- Cell Line
- Cell Membrane
- Corticotropin-Releasing Hormone -- agonists
- Cyclic AMP -- metabolism
- GTP-Binding Protein alpha Subunits, Gi-Go -- metabolism
- GTP-Binding Protein alpha Subunits, Gs -- metabolism
- Humans
- Ligands
- Peptide Hormones
- Peptides
- Protein Binding
- Protein Conformation
- Receptors, Corticotropin-Releasing Hormone -- metabolism
- Signal Transduction
- Structure-Activity Relationship
- Urocortins
- CRF Receptor, Type 1
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Publication Type: Journal Article
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