Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1. [electronic resource]
Producer: 20200511Description: 2032-2042 p. digitalISSN:- 1091-6490
- Animals
- Antigens, Neoplasm -- genetics
- Apoptosis
- Biomarkers, Tumor -- genetics
- Bone Neoplasms -- drug therapy
- Carcinoma, Neuroendocrine -- drug therapy
- Cell Adhesion Molecules -- genetics
- Cell Movement
- Cell Proliferation
- Follow-Up Studies
- Gene Expression Regulation, Neoplastic
- Humans
- Male
- Mice
- Mice, Inbred NOD
- Mice, SCID
- Neoplasm Invasiveness
- Phenotype
- Poly (ADP-Ribose) Polymerase-1 -- antagonists & inhibitors
- Poly(ADP-ribose) Polymerase Inhibitors -- pharmacology
- Prognosis
- Prostatic Neoplasms, Castration-Resistant -- drug therapy
- Survival Rate
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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