Acute doxorubicin nephrotoxicity in rats with malignant neoplasm can be successfully treated with fullerenol C60(OH)24 via suppression of oxidative stress. [electronic resource]
Producer: 20090220Description: 742-9 p. digitalISSN:- 1734-1140
- Animals
- Antibiotics, Antineoplastic -- antagonists & inhibitors
- Body Weight -- drug effects
- Catalase -- metabolism
- Doxorubicin -- antagonists & inhibitors
- Female
- Free Radical Scavengers -- therapeutic use
- Fullerenes -- therapeutic use
- Glutathione -- metabolism
- Glutathione Reductase -- metabolism
- Kidney -- metabolism
- Kidney Diseases -- chemically induced
- L-Lactate Dehydrogenase -- metabolism
- Malondialdehyde -- metabolism
- Mammary Neoplasms, Animal -- complications
- Organ Size -- drug effects
- Oxidative Stress -- drug effects
- Rats
- Rats, Sprague-Dawley
- Superoxide Dismutase -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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