Modulation of endochondral ossification by MEK inhibitors PD0325901 and AZD6244 (Selumetinib). [electronic resource]
Producer: 20140909Description: 151-61 p. digitalISSN:- 1873-2763
- Animals
- Benzamides -- pharmacology
- Benzimidazoles -- pharmacology
- Bone Marrow Cells -- cytology
- Bony Callus -- drug effects
- Cartilage -- drug effects
- Cell Differentiation -- drug effects
- Chondrocytes -- drug effects
- Diphenylamine -- analogs & derivatives
- Fracture Healing -- drug effects
- MAP Kinase Signaling System -- drug effects
- Mice
- Mice, Inbred C57BL
- Mitogen-Activated Protein Kinase Kinases -- antagonists & inhibitors
- Osteoblasts -- cytology
- Osteoclasts -- drug effects
- Osteogenesis -- drug effects
- Osteoprotegerin -- blood
- Protein Kinase Inhibitors -- pharmacology
- RANK Ligand -- blood
- Sheep
- Skull -- cytology
- X-Ray Microtomography
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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