Nutlin-3 induces HO-1 expression by activating JNK in a transcription-independent manner of p53. [electronic resource]
Producer: 20140904Description: 761-8 p. digitalISSN:- 1791-2423
- Apoptosis -- genetics
- Cell Line, Tumor
- Gene Expression Regulation, Neoplastic
- Heme Oxygenase-1 -- biosynthesis
- Humans
- Imidazoles -- administration & dosage
- MAP Kinase Kinase 4 -- biosynthesis
- Phosphorylation
- Piperazines -- administration & dosage
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Proto-Oncogene Proteins c-mdm2 -- antagonists & inhibitors
- RNA, Small Interfering
- Reactive Oxygen Species -- metabolism
- Transcription, Genetic
- Tumor Suppressor Protein p53 -- genetics
- p38 Mitogen-Activated Protein Kinases -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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