Pathway-based identification of biomarkers for targeted therapeutics: personalized oncology with PI3K pathway inhibitors. [electronic resource]
Producer: 20110224Description: 43ra55 p. digitalISSN:- 1946-6242
- Adaptor Proteins, Signal Transducing
- Animals
- Basophils -- drug effects
- Biomarkers, Tumor -- metabolism
- Breast Neoplasms -- enzymology
- Cell Line, Tumor
- Computational Biology
- Cytoskeletal Proteins -- metabolism
- Enzyme Activation -- drug effects
- Epitopes -- immunology
- Humans
- Lung Neoplasms -- enzymology
- Mice
- Neoplasms -- drug therapy
- PTEN Phosphohydrolase -- metabolism
- Phosphatidylinositol 3-Kinase -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- Phosphoproteins -- metabolism
- Phosphoserine -- metabolism
- Precision Medicine
- Protein Kinase Inhibitors -- pharmacology
- Protein Stability -- drug effects
- Protein Transport -- drug effects
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction -- drug effects
- Subcellular Fractions -- drug effects
- Substrate Specificity -- drug effects
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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