Further studies on imidazo[4,5-b]pyridine AT1 angiotensin II receptor antagonists. Effects of the transformation of the 4-phenylquinoline backbone into 4-phenylisoquinolinone or 1-phenylindene scaffolds. [electronic resource]
Producer: 20061205Description: 6451-64 p. digitalISSN:- 0022-2623
- Angiotensin II Type 1 Receptor Blockers -- chemistry
- Animals
- Caco-2 Cells
- Computer Simulation
- Crystallography, X-Ray
- Humans
- Hydrogenation
- In Vitro Techniques
- Indenes -- chemistry
- Indicators and Reagents
- Intestinal Absorption
- Isoquinolines -- chemistry
- Magnetic Resonance Spectroscopy
- Male
- Models, Molecular
- Predictive Value of Tests
- Purines -- chemistry
- Quinolones -- chemistry
- Rabbits
- Rats
- Rats, Sprague-Dawley
- Rats, Wistar
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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