Translational exposure-efficacy modeling to optimize the dose and schedule of taxanes combined with the investigational Aurora A kinase inhibitor MLN8237 (alisertib). [electronic resource]
Producer: 20151117Description: 2170-83 p. digitalISSN:- 1538-8514
- Animals
- Antineoplastic Agents -- administration & dosage
- Area Under Curve
- Aurora Kinase A -- antagonists & inhibitors
- Azepines -- administration & dosage
- Cell Line, Tumor
- Docetaxel
- Drug Administration Schedule
- Female
- Humans
- Mice
- Mice, Inbred BALB C
- Mice, SCID
- Neoplasm Transplantation
- Neoplasms, Experimental -- drug therapy
- Paclitaxel -- administration & dosage
- Pyrimidines -- administration & dosage
- Taxoids -- administration & dosage
- Translational Research, Biomedical
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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