Targeting the Regulatory Site of ER Aminopeptidase 1 Leads to the Discovery of a Natural Product Modulator of Antigen Presentation. [electronic resource]
Producer: 20200914Description: 3348-3358 p. digitalISSN:- 1520-4804
- Allosteric Site
- Aminopeptidases -- antagonists & inhibitors
- Animals
- Antigen Presentation -- drug effects
- Catalytic Domain
- Crystallography, X-Ray
- Diterpenes, Clerodane -- chemistry
- Enzyme Activators -- chemistry
- Epitopes -- chemistry
- HeLa Cells
- Humans
- Mice
- Minor Histocompatibility Antigens -- chemistry
- Peptides -- chemistry
- Protease Inhibitors -- chemistry
- Protein Binding
- Proteolysis -- drug effects
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Publication Type: Journal Article
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