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Mutations in the phosphatidylinositol-3-kinase pathway predict for antitumor activity of the inhibitor PX-866 whereas oncogenic Ras is a dominant predictor for resistance. [electronic resource] by
- Ihle, Nathan T
- Lemos, Robert
- Wipf, Peter
- Yacoub, Adly
- Mitchell, Clint
- Siwak, Doris
- Mills, Gordon B
- Dent, Paul
- Kirkpatrick, D Lynn
- Powis, Garth
Producer: 20090130
In:
Cancer research vol. 69
Availability: No items available.
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Cellular and in vivo activity of a novel PI3K inhibitor, PX-866, against human glioblastoma. [electronic resource] by
- Koul, Dimpy
- Shen, Ruijun
- Kim, Yong-Wan
- Kondo, Yasuko
- Lu, Yiling
- Bankson, Jim
- Ronen, Sabrina M
- Kirkpatrick, D Lynn
- Powis, Garth
- Yung, W K Alfred
Producer: 20110222
In:
Neuro-oncology vol. 12
Availability: No items available.
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16.
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A Phase I pharmacokinetic and pharmacodynamic study of PX-12, a novel inhibitor of thioredoxin-1, in patients with advanced solid tumors. [electronic resource] by
- Ramanathan, Ramesh K
- Kirkpatrick, D Lynn
- Belani, Chandra P
- Friedland, David
- Green, Sylvan B
- Chow, H-H Sherry
- Cordova, Catherine A
- Stratton, Steven P
- Sharlow, Elizabeth R
- Baker, Amanda
- Dragovich, Tomislav
Producer: 20070621
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 13
Availability: No items available.
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Molecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor. [electronic resource] by
- Meuillet, Emmanuelle J
- Zuohe, Song
- Lemos, Robert
- Ihle, Nathan
- Kingston, John
- Watkins, Ryan
- Moses, Sylvestor A
- Zhang, Shuxing
- Du-Cuny, Lei
- Herbst, Roy
- Jacoby, Jörg J
- Zhou, Li Li
- Ahad, Ali M
- Mash, Eugene A
- Kirkpatrick, D Lynn
- Powis, Garth
Producer: 20100618
In:
Molecular cancer therapeutics vol. 9
Availability: No items available.
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