Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches. [electronic resource]
Producer: 20100323Description: 1810-8 p. digitalISSN:- 1520-4804
- Binding Sites
- Binding, Competitive
- Combinatorial Chemistry Techniques
- Crystallography, X-Ray
- Humans
- Jumonji Domain-Containing Histone Demethylases -- antagonists & inhibitors
- Models, Molecular
- Oxalates -- chemical synthesis
- Spectrometry, Mass, Electrospray Ionization
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- Structure-Activity Relationship
- Tyrosine -- analogs & derivatives
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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