Statin-mediated cytoprotection of human vascular endothelial cells: a role for Kruppel-like factor 2-dependent induction of heme oxygenase-1. [electronic resource]
Producer: 20080108Description: 2537-46 p. digitalISSN:- 1538-7933
- Antioxidants -- pharmacology
- Atorvastatin
- Bilirubin -- metabolism
- Biliverdine -- metabolism
- Cell Survival -- drug effects
- Cells, Cultured
- Cytoprotection
- Dose-Response Relationship, Drug
- Endothelial Cells -- drug effects
- Enzyme Induction
- Enzyme Inhibitors -- pharmacology
- Ferritins -- genetics
- Heme Oxygenase-1 -- antagonists & inhibitors
- Heptanoic Acids -- pharmacology
- Humans
- Hydrogen Peroxide -- pharmacology
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Iron Chelating Agents -- pharmacology
- Kruppel-Like Transcription Factors -- genetics
- Mevalonic Acid -- pharmacology
- Oxidants -- pharmacology
- Oxidative Stress -- drug effects
- Prenylation
- Promoter Regions, Genetic -- drug effects
- Protoporphyrins -- pharmacology
- Pyrroles -- pharmacology
- RNA Interference
- RNA, Messenger -- biosynthesis
- RNA, Small Interfering -- metabolism
- Reactive Oxygen Species -- metabolism
- Terpenes -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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