Coiled-coil structure-dependent interactions between polyQ proteins and Foxo lead to dendrite pathology and behavioral defects. [electronic resource]
Producer: 20190503Description: E10748-E10757 p. digitalISSN:- 1091-6490
- Amino Acid Sequence
- Animals
- Ataxin-3 -- chemistry
- Behavior, Animal
- Binding Sites
- Cell Nucleus -- metabolism
- Disease Models, Animal
- Drosophila Proteins -- chemistry
- Drosophila melanogaster -- genetics
- Forkhead Transcription Factors -- chemistry
- Humans
- Mutation
- Neurons -- metabolism
- Peptides -- chemistry
- Protein Binding
- Protein Conformation, alpha-Helical
- Protein Conformation, beta-Strand
- Protein Interaction Domains and Motifs
- Spinocerebellar Ataxias -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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