Synthesis and SAR of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones related to licostinel (Acea 1021) as NMDA/glycine site antagonists. [electronic resource]
Producer: 20040106Description: 1769-80 p. digitalISSN:- 0968-0896
- Animals
- Binding Sites
- Cell Membrane -- drug effects
- Cerebral Cortex -- metabolism
- Glycine -- antagonists & inhibitors
- Inhibitory Concentration 50
- Kynurenic Acid -- analogs & derivatives
- Quinoxalines -- chemical synthesis
- Radioligand Assay
- Rats
- Receptors, N-Methyl-D-Aspartate -- antagonists & inhibitors
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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