Aminoglycoside binding in the major groove of duplex RNA: the thermodynamic and electrostatic forces that govern recognition. [electronic resource]
Producer: 20000510Description: 95-110 p. digitalISSN:- 0022-2836
- Anti-Bacterial Agents -- chemistry
- Base Pairing -- drug effects
- Binding Sites
- Calorimetry
- Circular Dichroism
- Computer Simulation
- Hydrogen Bonding
- Hydrogen-Ion Concentration
- Models, Molecular
- Molecular Weight
- Nucleic Acid Conformation -- drug effects
- Nucleic Acid Denaturation -- drug effects
- Protons
- RNA Stability -- drug effects
- RNA, Double-Stranded -- chemistry
- Sodium -- pharmacology
- Spectrophotometry, Ultraviolet
- Static Electricity
- Substrate Specificity
- Thermodynamics
- Titrimetry
- Tobramycin -- chemistry
- Viscosity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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