Chalcones bearing a 3,4,5-trimethoxyphenyl motif are capable of selectively inhibiting oncogenic K-Ras signaling. [electronic resource]
Producer: 20210430Description: 127144 p. digitalISSN:- 1464-3405
- Animals
- Antineoplastic Agents -- chemistry
- Cell Line, Tumor
- Chalcones -- chemistry
- Dogs
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Humans
- Madin Darby Canine Kidney Cells
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction -- drug effects
- ras Proteins -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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