A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function. [electronic resource]
Producer: 20070319Description: 2163-75 p. digitalISSN:- 1529-2401
- Animals
- Base Sequence
- Chromosome Mapping
- Deafness -- chemically induced
- Disease Models, Animal
- Ethylnitrosourea -- analogs & derivatives
- Female
- Genes, Recessive
- Genetic Testing
- Hair Cells, Auditory, Outer -- cytology
- Humans
- Male
- Membrane Proteins -- genetics
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mutagens
- Neoplasm Proteins -- metabolism
- Pedigree
- Point Mutation
- Psychomotor Agitation -- genetics
- Sequence Alignment
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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