Daidzein suppresses pro-inflammatory chemokine Cxcl2 transcription in TNF-α-stimulated murine lung epithelial cells via depressing PARP-1 activity. [electronic resource]
Producer: 20150406Description: 496-503 p. digitalISSN:- 1745-7254
- Animals
- Anti-Inflammatory Agents -- pharmacology
- Cell Line
- Chemokine CXCL2 -- genetics
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Down-Regulation
- Enzyme Inhibitors -- pharmacology
- Epithelial Cells -- drug effects
- Genes, Reporter
- Isoflavones -- pharmacology
- Lung -- drug effects
- Male
- Mice, Inbred C57BL
- Pneumonia -- chemically induced
- Poly (ADP-Ribose) Polymerase-1
- Poly(ADP-ribose) Polymerase Inhibitors
- Poly(ADP-ribose) Polymerases -- genetics
- RNA, Messenger -- metabolism
- Signal Transduction -- drug effects
- Time Factors
- Transcription Factor RelA -- genetics
- Transcription, Genetic -- drug effects
- Transfection
- Tumor Necrosis Factor-alpha
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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