Results
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Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1. [electronic resource] by
- Luptak, Jakub
- Bista, Michal
- Fisher, David
- Flavell, Liz
- Gao, Ning
- Wickson, Kate
- Kazmirski, Steven L
- Howard, Tina
- Rawlins, Philip B
- Hargreaves, David
Producer: 20200224
In:
Acta crystallographica. Section D, Structural biology vol. 75
Availability: No items available.
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The mechanism of ATP-dependent primer-template recognition by a clamp loader complex. [electronic resource] by
- Simonetta, Kyle R
- Kazmirski, Steven L
- Goedken, Eric R
- Cantor, Aaron J
- Kelch, Brian A
- McNally, Randall
- Seyedin, Steven N
- Makino, Debora L
- O'Donnell, Mike
- Kuriyan, John
Producer: 20090604
In:
Cell vol. 137
Availability: No items available.
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Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. [electronic resource] by
- Cocozaki, Alexis I
- Altman, Roger B
- Huang, Jian
- Buurman, Ed T
- Kazmirski, Steven L
- Doig, Peter
- Prince, D Bryan
- Blanchard, Scott C
- Cate, Jamie H D
- Ferguson, Andrew D
Producer: 20171127
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 113
Availability: No items available.
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Beyond the MEK-pocket: can current MEK kinase inhibitors be utilized to synthesize novel type III NCKIs? Does the MEK-pocket exist in kinases other than MEK? [electronic resource] by
- Tecle, Haile
- Shao, Jianxing
- Li, Yanhong
- Kothe, Michael
- Kazmirski, Steven
- Penzotti, Julie
- Ding, Yuan-Hua
- Ohren, Jeffrey
- Moshinsky, Deb
- Coli, Rocco
- Jhawar, Nidhi
- Bora, Emilia
- Jacques-O'Hagan, Suzanne
- Wu, Joe
Producer: 20090128
In:
Bioorganic & medicinal chemistry letters vol. 19
Availability: No items available.
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Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping. [electronic resource] by
- Doig, Peter
- Boriack-Sjodin, P Ann
- Dumas, Jacques
- Hu, Jun
- Itoh, Kenji
- Johnson, Kenneth
- Kazmirski, Steven
- Kinoshita, Tomohiko
- Kuroda, Satoru
- Sato, Tomo-o
- Sugimoto, Kaori
- Tohyama, Katsumi
- Aoi, Hiroshi
- Wakamatsu, Kazusa
- Wang, Hongming
Producer: 20150716
In:
Bioorganic & medicinal chemistry vol. 22
Availability: No items available.
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Enhanced selectivity profile of pyrazole-urea based DFG-out p38alpha inhibitors. [electronic resource] by
- Liu, Hu
- Kuhn, Cyrille
- Feru, Frederic
- Jacques, Suzanne L
- Deshmukh, Gayatri D
- Ye, Ping
- Rennie, Glen R
- Johnson, Theresa
- Kazmirski, Steven
- Low, Simon
- Coli, Rocco
- Ding, Yuan-hua
- Cheng, Alan C
- Tecle, Haile
- English, Jessie M
- Stanton, Robert
- Wu, Joe C
Producer: 20101110
In:
Bioorganic & medicinal chemistry letters vol. 20
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Modulating the strength of hydrogen bond acceptors to achieve low Caco2 efflux for oral bioavailability of PARP inhibitors blocking centrosome clustering. [electronic resource] by
- Gu, Chungang
- Lamb, Michelle L
- Johannes, Jeffrey W
- Sylvester, Mark A
- Eisman, Mark S
- Harrison, Rane A
- Hu, Haiqing
- Kazmirski, Steven
- Mikule, Keith
- Peng, Bo
- Su, Nancy
- Wang, Wenxian
- Ye, Qing
- Zheng, Xiaolan
- Lyne, Paul D
- Scott, David A
Producer: 20170717
In:
Bioorganic & medicinal chemistry letters vol. 26
Availability: No items available.
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The design, synthesis and potential utility of fluorescence probes that target DFG-out conformation of p38alpha for high throughput screening binding assay. [electronic resource] by
- Tecle, Haile
- Feru, Frederic
- Liu, Hu
- Kuhn, Cyrille
- Rennie, Glen
- Morris, Mark
- Shao, Jiangxing
- Cheng, Alan C
- Gikunju, Diana
- Miret, Juan
- Coli, Rocco
- Xi, Simon Hualin
- Clugston, Susan L
- Low, Simon
- Kazmirski, Steven
- Ding, Yuan-Hua
- Cao, Qing
- Johnson, Theresa L
- Deshmukh, Gayatri D
- DiNitto, Jonathan P
- Wu, Joe C
- English, Jessie M
Producer: 20100122
In:
Chemical biology & drug design vol. 74
Availability: No items available.
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Discovery of novel, potent, and selective inhibitors of 3-phosphoinositide-dependent kinase (PDK1). [electronic resource] by
- Murphy, Sean T
- Alton, Gordon
- Bailey, Simon
- Baxi, Sangita M
- Burke, Benjamin J
- Chappie, Thomas A
- Ermolieff, Jacques
- Ferre, RoseAnn
- Greasley, Samantha
- Hickey, Michael
- Humphrey, John
- Kablaoui, Natasha
- Kath, John
- Kazmirski, Steven
- Kraus, Michelle
- Kupchinsky, Stan
- Li, John
- Lingardo, Laura
- Marx, Matthew A
- Richter, Dan
- Tanis, Steven P
- Tran, Khanh
- Vernier, William
- Xie, Zhi
- Yin, Min-Jean
- Yu, Xiao-Hong
Producer: 20120308
In:
Journal of medicinal chemistry vol. 54
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Discovery of AZ0108, an orally bioavailable phthalazinone PARP inhibitor that blocks centrosome clustering. [electronic resource] by
- Johannes, Jeffrey W
- Almeida, Lynsie
- Daly, Kevin
- Ferguson, Andrew D
- Grosskurth, Shaun E
- Guan, Huiping
- Howard, Tina
- Ioannidis, Stephanos
- Kazmirski, Steven
- Lamb, Michelle L
- Larsen, Nicholas A
- Lyne, Paul D
- Mikule, Keith
- Ogoe, Claude
- Peng, Bo
- Petteruti, Philip
- Read, Jon A
- Su, Nancy
- Sylvester, Mark
- Throner, Scott
- Wang, Wenxian
- Wang, Xin
- Wu, Jiaquan
- Ye, Qing
- Yu, Yan
- Zheng, Xiaolan
- Scott, David A
Producer: 20160829
In:
Bioorganic & medicinal chemistry letters vol. 25
Availability: No items available.
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Pyrimidinone nicotinamide mimetics as selective tankyrase and wnt pathway inhibitors suitable for in vivo pharmacology. [electronic resource] by
- Johannes, Jeffrey W
- Almeida, Lynsie
- Barlaam, Bernard
- Boriack-Sjodin, P Ann
- Casella, Robert
- Croft, Rosemary A
- Dishington, Allan P
- Gingipalli, Lakshmaiah
- Gu, Chungang
- Hawkins, Janet L
- Holmes, Jane L
- Howard, Tina
- Huang, Jian
- Ioannidis, Stephanos
- Kazmirski, Steven
- Lamb, Michelle L
- McGuire, Thomas M
- Moore, Jane E
- Ogg, Derek
- Patel, Anil
- Pike, Kurt G
- Pontz, Timothy
- Robb, Graeme R
- Su, Nancy
- Wang, Haiyun
- Wu, Xiaoyun
- Zhang, Hai-Jun
- Zhang, Yue
- Zheng, Xiaolan
- Wang, Tao
Producer: 20150327
In:
ACS medicinal chemistry letters vol. 6
Availability: No items available.
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