SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age. [electronic resource]
Producer: 20150720Description: 5011 p. digitalISSN:- 2041-1723
- Aging -- physiology
- Animals
- Chromatin Immunoprecipitation
- DNA Primers -- genetics
- Heterochromatin -- metabolism
- Immunoprecipitation
- Long Interspersed Nucleotide Elements -- genetics
- Luciferases
- Mice
- Mice, Knockout
- Nuclear Proteins -- metabolism
- Real-Time Polymerase Chain Reaction
- Repressor Proteins -- metabolism
- Sirtuins -- genetics
- Stress, Physiological -- physiology
- Sulfites
- Tripartite Motif-Containing Protein 28
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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