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Telavancin, a multifunctional lipoglycopeptide, disrupts both cell wall synthesis and cell membrane integrity in methicillin-resistant Staphylococcus aureus. [electronic resource] by
- Higgins, Deborah L
- Chang, Ray
- Debabov, Dmitri V
- Leung, Joey
- Wu, Terry
- Krause, Kevin M
- Sandvik, Erik
- Hubbard, Jeffrey M
- Kaniga, Koné
- Schmidt, Donald E
- Gao, Qiufeng
- Cass, Robert T
- Karr, Dane E
- Benton, Bret M
- Humphrey, Patrick P
Producer: 20050509
In:
Antimicrobial agents and chemotherapy vol. 49
Availability: No items available.
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The Irreversible Covalent Fibroblast Growth Factor Receptor Inhibitor PRN1371 Exhibits Sustained Inhibition of FGFR after Drug Clearance. [electronic resource] by
- Venetsanakos, Eleni
- Brameld, Ken A
- Phan, Vernon T
- Verner, Erik
- Owens, Timothy D
- Xing, Yan
- Tam, Danny
- LaStant, Jacob
- Leung, Kwan
- Karr, Dane E
- Hill, Ronald J
- Gerritsen, Mary E
- Goldstein, David M
- Funk, Jens Oliver
- Bradshaw, J Michael
Producer: 20180807
In:
Molecular cancer therapeutics vol. 16
Availability: No items available.
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Discovery of the Irreversible Covalent FGFR Inhibitor 8-(3-(4-Acryloylpiperazin-1-yl)propyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (PRN1371) for the Treatment of Solid Tumors. [electronic resource] by
- Brameld, Ken A
- Owens, Timothy D
- Verner, Erik
- Venetsanakos, Eleni
- Bradshaw, J Michael
- Phan, Vernon T
- Tam, Danny
- Leung, Kwan
- Shu, Jin
- LaStant, Jacob
- Loughhead, David G
- Ton, Tony
- Karr, Dane E
- Gerritsen, Mary E
- Goldstein, David M
- Funk, Jens Oliver
Producer: 20170905
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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Hydrophobic vancomycin derivatives with improved ADME properties: discovery of telavancin (TD-6424). [electronic resource] by
- Leadbetter, Michael R
- Adams, Stacy M
- Bazzini, Bettina
- Fatheree, Paul R
- Karr, Dane E
- Krause, Kevin M
- Lam, Bernice M T
- Linsell, Martin S
- Nodwell, Matthew B
- Pace, John L
- Quast, Kelly
- Shaw, Jeng-Pyng
- Soriano, Elizabeth
- Trapp, Sean G
- Villena, Jenny D
- Wu, Terry X
- Christensen, Burton G
- Judice, J Kevin
Producer: 20040903
In:
The Journal of antibiotics vol. 57
Availability: No items available.
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Prolonged and tunable residence time using reversible covalent kinase inhibitors. [electronic resource] by
- Bradshaw, J Michael
- McFarland, Jesse M
- Paavilainen, Ville O
- Bisconte, Angelina
- Tam, Danny
- Phan, Vernon T
- Romanov, Sergei
- Finkle, David
- Shu, Jin
- Patel, Vaishali
- Ton, Tony
- Li, Xiaoyan
- Loughhead, David G
- Nunn, Philip A
- Karr, Dane E
- Gerritsen, Mary E
- Funk, Jens Oliver
- Owens, Timothy D
- Verner, Erik
- Brameld, Ken A
- Hill, Ronald J
- Goldstein, David M
- Taunton, Jack
Producer: 20150826
In:
Nature chemical biology vol. 11
Availability: No items available.
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