Revisiting an old antimicrobial drug: amphotericin B induces interleukin-1-converting enzyme as the main factor for inducible nitric-oxide synthase expression in activated endothelia. [electronic resource]
Producer: 20021011Description: 936-46 p. digitalISSN:- 0026-895X
- Amphotericin B -- pharmacology
- Animals
- Antifungal Agents -- pharmacology
- Caspase 1 -- biosynthesis
- Cytokines -- metabolism
- Endothelium, Vascular -- drug effects
- Enzyme Induction -- drug effects
- Gene Expression -- drug effects
- Humans
- Interleukin-1 -- metabolism
- Nitric Oxide Synthase -- biosynthesis
- Nitric Oxide Synthase Type II
- Promoter Regions, Genetic -- physiology
- RNA, Messenger -- biosynthesis
- Rats
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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