Results
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Synthesis and structure-activity relationship of 2-arylamino-4-aryl-pyrimidines as potent PAK1 inhibitors. [electronic resource] by
- Xu, Yong
- Foulks, Jason M
- Clifford, Adrianne
- Brenning, Benjamin
- Lai, Shuping
- Luo, Bai
- Parnell, K Mark
- Merx, Shannon
- McCullar, Michael V
- Kanner, Steven B
- Ho, Koc-Kan
Producer: 20140121
In:
Bioorganic & medicinal chemistry letters vol. 23
Availability: No items available.
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4.
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Synthesis and Biological Evaluation of Pyrazolo[1,5-a]pyrimidine Compounds as Potent and Selective Pim-1 Inhibitors. [electronic resource] by
- Xu, Yong
- Brenning, Benjamin G
- Kultgen, Steven G
- Foulks, Jason M
- Clifford, Adrianne
- Lai, Shuping
- Chan, Ashley
- Merx, Shannon
- McCullar, Michael V
- Kanner, Steven B
- Ho, Koc-Kan
Producer: 20150115
In:
ACS medicinal chemistry letters vol. 6
Availability: No items available.
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5.
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Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. [electronic resource] by
- Ho, Koc-Kan
- Parnell, K Mark
- Yuan, Yi
- Xu, Yong
- Kultgen, Steven G
- Hamblin, Steven
- Hendrickson, Thomas F
- Luo, Bai
- Foulks, Jason M
- McCullar, Michael V
- Kanner, Steven B
Producer: 20130701
In:
Bioorganic & medicinal chemistry letters vol. 23
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6.
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Epigenetic drug discovery: targeting DNA methyltransferases. [electronic resource] by
- Foulks, Jason M
- Parnell, K Mark
- Nix, Rebecca N
- Chau, Suzanna
- Swierczek, Krzysztof
- Saunders, Michael
- Wright, Kevin
- Hendrickson, Thomas F
- Ho, Koc-Kan
- McCullar, Michael V
- Kanner, Steven B
Producer: 20120625
In:
Journal of biomolecular screening vol. 17
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Monoclonal antibodies to six-transmembrane epithelial antigen of the prostate-1 inhibit intercellular communication in vitro and growth of human tumor xenografts in vivo. [electronic resource] by
- Challita-Eid, Pia M
- Morrison, Kendall
- Etessami, Soudabeh
- An, Zili
- Morrison, Karen J
- Perez-Villar, Juan J
- Raitano, Arthur B
- Jia, Xiao-Chi
- Gudas, Jean M
- Kanner, Steven B
- Jakobovits, Aya
Producer: 20070925
In:
Cancer research vol. 67
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8.
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Phosphorylation-specific status of RNAi triggers in pharmacokinetic and biodistribution analyses. [electronic resource] by
- Trubetskoy, Vladimir S
- Griffin, Jacob B
- Nicholas, Anthony L
- Nord, Eric M
- Xu, Zhao
- Peterson, Ryan M
- Wooddell, Christine I
- Rozema, David B
- Wakefield, Darren H
- Lewis, David L
- Kanner, Steven B
Producer: 20171030
In:
Nucleic acids research vol. 45
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9.
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Discovery of 3-(trifluoromethyl)-1H-pyrazole-5-carboxamide activators of the M2 isoform of pyruvate kinase (PKM2). [electronic resource] by
- Xu, Yong
- Liu, Xiao-Hui
- Saunders, Michael
- Pearce, Scott
- Foulks, Jason M
- Parnell, K Mark
- Clifford, Adrianne
- Nix, Rebecca N
- Bullough, Jeremy
- Hendrickson, Thomas F
- Wright, Kevin
- McCullar, Michael V
- Kanner, Steven B
- Ho, Koc-Kan
Producer: 20140826
In:
Bioorganic & medicinal chemistry letters vol. 24
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10.
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Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56(Lck). [electronic resource] by
- Wityak, John
- Das, Jagabandhu
- Moquin, Robert V
- Shen, Zhongqi
- Lin, James
- Chen, Ping
- Doweyko, Arthur M
- Pitt, Sidney
- Pang, Suhong
- Shen, Ding Ren
- Fang, Qiong
- de Fex, Henry F
- Schieven, Gary L
- Kanner, Steven B
- Barrish, Joel C
Producer: 20040706
In:
Bioorganic & medicinal chemistry letters vol. 13
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11.
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HIF2α-Targeted RNAi Therapeutic Inhibits Clear Cell Renal Cell Carcinoma. [electronic resource] by
- Wong, So C
- Cheng, Weijun
- Hamilton, Holly
- Nicholas, Anthony L
- Wakefield, Darren H
- Almeida, Aaron
- Blokhin, Andrei V
- Carlson, Jeffrey
- Neal, Zane C
- Subbotin, Vladimir
- Zhang, Guofeng
- Hegge, Julia
- Bertin, Stephanie
- Trubetskoy, Vladimir S
- Rozema, David B
- Lewis, David L
- Kanner, Steven B
Producer: 20190305
In:
Molecular cancer therapeutics vol. 17
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12.
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RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg. [electronic resource] by
- Wooddell, Christine I
- Yuen, Man-Fung
- Chan, Henry Lik-Yuen
- Gish, Robert G
- Locarnini, Stephen A
- Chavez, Deborah
- Ferrari, Carlo
- Given, Bruce D
- Hamilton, James
- Kanner, Steven B
- Lai, Ching-Lung
- Lau, Johnson Y N
- Schluep, Thomas
- Xu, Zhao
- Lanford, Robert E
- Lewis, David L
Producer: 20180528
In:
Science translational medicine vol. 9
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13.
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Pharmacologic activation of PKM2 slows lung tumor xenograft growth. [electronic resource] by
- Parnell, K Mark
- Foulks, Jason M
- Nix, Rebecca N
- Clifford, Adrianne
- Bullough, Jeremy
- Luo, Bai
- Senina, Anna
- Vollmer, David
- Liu, Jihua
- McCarthy, Virgil
- Xu, Yong
- Saunders, Michael
- Liu, Xiao-Hui
- Pearce, Scott
- Wright, Kevin
- O'Reilly, Marc
- McCullar, Michael V
- Ho, Koc-Kan
- Kanner, Steven B
Producer: 20140401
In:
Molecular cancer therapeutics vol. 12
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14.
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Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors. [electronic resource] by
- Das, Jagabandhu
- Liu, Chunjian
- Moquin, Robert V
- Lin, James
- Furch, Joseph A
- Spergel, Steven H
- Doweyko, Arthur M
- McIntyre, Kim W
- Shuster, David J
- O'Day, Kathleen D
- Penhallow, Becky
- Hung, Chen-Yi
- Kanner, Steven B
- Lin, Tai-An
- Dodd, John H
- Barrish, Joel C
- Wityak, John
Producer: 20060626
In:
Bioorganic & medicinal chemistry letters vol. 16
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15.
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Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors. [electronic resource] by
- Das, Jagabandhu
- Furch, Joseph A
- Liu, Chunjian
- Moquin, Robert V
- Lin, James
- Spergel, Steven H
- McIntyre, Kim W
- Shuster, David J
- O'Day, Kathleen D
- Penhallow, Becky
- Hung, Chen-Yi
- Doweyko, Arthur M
- Kamath, Amrita
- Zhang, Hongjian
- Marathe, Punit
- Kanner, Steven B
- Lin, Tai-An
- Dodd, John H
- Barrish, Joel C
- Wityak, John
Producer: 20060925
In:
Bioorganic & medicinal chemistry letters vol. 16
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16.
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A small-molecule inhibitor of PIM kinases as a potential treatment for urothelial carcinomas. [electronic resource] by
- Foulks, Jason M
- Carpenter, Kent J
- Luo, Bai
- Xu, Yong
- Senina, Anna
- Nix, Rebecca
- Chan, Ashley
- Clifford, Adrianne
- Wilkes, Marcus
- Vollmer, David
- Brenning, Benjamin
- Merx, Shannon
- Lai, Shuping
- McCullar, Michael V
- Ho, Koc-Kan
- Albertson, Daniel J
- Call, Lee T
- Bearss, Jared J
- Tripp, Sheryl
- Liu, Ting
- Stephens, Bret J
- Mollard, Alexis
- Warner, Steven L
- Bearss, David J
- Kanner, Steven B
Producer: 20150305
In:
Neoplasia (New York, N.Y.) vol. 16
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17.
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Imidazoquinoxaline Src-family kinase p56Lck inhibitors: SAR, QSAR, and the discovery of (S)-N-(2-chloro-6-methylphenyl)-2-(3-methyl-1-piperazinyl)imidazo- [1,5-a]pyrido[3,2-e]pyrazin-6-amine (BMS-279700) as a potent and orally active inhibitor with excellent in vivo antiinflammatory activity. [electronic resource] by
- Chen, Ping
- Doweyko, Arthur M
- Norris, Derek
- Gu, Henry H
- Spergel, Steven H
- Das, Jagabundhu
- Moquin, Robert V
- Lin, James
- Wityak, John
- Iwanowicz, Edwin J
- McIntyre, Kim W
- Shuster, David J
- Behnia, Kamelia
- Chong, Saeho
- de Fex, Henry
- Pang, Suhong
- Pitt, Sydney
- Shen, Ding Ren
- Thrall, Sara
- Stanley, Paul
- Kocy, Octavian R
- Witmer, Mark R
- Kanner, Steven B
- Schieven, Gary L
- Barrish, Joel C
Producer: 20040924
In:
Journal of medicinal chemistry vol. 47
Availability: No items available.
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18.
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Selective Itk inhibitors block T-cell activation and murine lung inflammation. [electronic resource] by
- Lin, Tai-An
- McIntyre, Kim W
- Das, Jagabandhu
- Liu, Chunjian
- O'Day, Kathleen D
- Penhallow, Becky
- Hung, Chen-Yi
- Whitney, Gena S
- Shuster, David J
- Yang, XiaoXia
- Townsend, Robert
- Postelnek, Jennifer
- Spergel, Steven H
- Lin, James
- Moquin, Robert V
- Furch, Joseph A
- Kamath, Amrita V
- Zhang, Hongjian
- Marathe, Punit H
- Perez-Villar, Juan J
- Doweyko, Arthur
- Killar, Loran
- Dodd, John H
- Barrish, Joel C
- Wityak, John
- Kanner, Steven B
Producer: 20041005
In:
Biochemistry vol. 43
Availability: No items available.
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19.
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Design, synthesis, and anti-inflammatory properties of orally active 4-(phenylamino)-pyrrolo[2,1-f][1,2,4]triazine p38alpha mitogen-activated protein kinase inhibitors. [electronic resource] by
- Hynes, John
- Dyckman, Alaric J
- Lin, Shuqun
- Wrobleski, Stephen T
- Wu, Hong
- Gillooly, Kathleen M
- Kanner, Steven B
- Lonial, Herinder
- Loo, Derek
- McIntyre, Kim W
- Pitt, Sidney
- Shen, Ding Ren
- Shuster, David J
- Yang, Xiaoxia
- Zhang, Rosemary
- Behnia, Kamelia
- Zhang, Hongjian
- Marathe, Punit H
- Doweyko, Arthur M
- Tokarski, John S
- Sack, John S
- Pokross, Matthew
- Kiefer, Susan E
- Newitt, John A
- Barrish, Joel C
- Dodd, John
- Schieven, Gary L
- Leftheris, Katerina
Producer: 20080227
In:
Journal of medicinal chemistry vol. 51
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20.
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Harnessing type I CRISPR-Cas systems for genome engineering in human cells. [electronic resource] by
- Cameron, Peter
- Coons, Mary M
- Klompe, Sanne E
- Lied, Alexandra M
- Smith, Stephen C
- Vidal, Bastien
- Donohoue, Paul D
- Rotstein, Tomer
- Kohrs, Bryan W
- Nyer, David B
- Kennedy, Rachel
- Banh, Lynda M
- Williams, Carolyn
- Toh, Mckenzi S
- Irby, Matthew J
- Edwards, Leslie S
- Lin, Chun-Han
- Owen, Arthur L G
- Künne, Tim
- van der Oost, John
- Brouns, Stan J J
- Slorach, Euan M
- Fuller, Chris K
- Gradia, Scott
- Kanner, Steven B
- May, Andrew P
- Sternberg, Samuel H
Producer: 20200128
In:
Nature biotechnology vol. 37
Availability: No items available.
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