Integrated next-generation sequencing and avatar mouse models for personalized cancer treatment. [electronic resource]
Producer: 20150820Description: 2476-84 p. digitalISSN:- 1557-3265
- Adult
- Aged
- Animals
- Antineoplastic Agents -- administration & dosage
- Computational Biology
- DNA Copy Number Variations
- Disease Models, Animal
- Exome
- Extracellular Signal-Regulated MAP Kinases -- antagonists & inhibitors
- Female
- Genomics
- High-Throughput Nucleotide Sequencing
- Humans
- Male
- Mice
- Middle Aged
- Models, Molecular
- Molecular Targeted Therapy
- Mutation
- Neoplasms -- drug therapy
- Phosphatidylinositol 3-Kinases -- chemistry
- Phosphoinositide-3 Kinase Inhibitors
- Precision Medicine
- Protein Conformation
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Retrospective Studies
- Treatment Outcome
- Tumor Burden
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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