BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-beta 1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression. [electronic resource]
Producer: 20031007Description: 34387-94 p. digitalISSN:- 0021-9258
- Alkaline Phosphatase -- metabolism
- Animals
- Blotting, Northern
- Blotting, Southern
- Blotting, Western
- Bone Morphogenetic Protein 2
- Bone Morphogenetic Proteins -- metabolism
- Cell Differentiation
- Cell Line
- Core Binding Factor Alpha 1 Subunit
- Cycloheximide -- pharmacology
- Dose-Response Relationship, Drug
- Down-Regulation
- Homeodomain Proteins -- metabolism
- Mice
- Neoplasm Proteins
- Osteoblasts -- cytology
- Plasmids -- metabolism
- Protein Synthesis Inhibitors -- pharmacology
- RNA -- metabolism
- Rats
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction
- Transcription Factors -- biosynthesis
- Transfection
- Transforming Growth Factor beta -- metabolism
- Transforming Growth Factor beta1
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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