Aneuploid human colonic epithelial cells are sensitive to AICAR-induced growth inhibition through EGFR degradation. [electronic resource]
Producer: 20130903Description: 3139-46 p. digitalISSN:- 1476-5594
- Aminoimidazole Carboxamide -- analogs & derivatives
- Aneuploidy
- Animals
- Antineoplastic Agents -- pharmacology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Colon -- drug effects
- Colorectal Neoplasms -- drug therapy
- Epithelial Cells -- drug effects
- ErbB Receptors -- metabolism
- Humans
- Hypoglycemic Agents -- pharmacology
- Intestinal Mucosa -- drug effects
- Leupeptins -- pharmacology
- Mice
- Neoplasm Transplantation
- Proteasome Endopeptidase Complex -- metabolism
- Ribonucleotides -- pharmacology
- Transplantation, Heterologous
- Trisomy
- Ubiquitination
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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