Decreased mRNA and protein stability of W1282X limits response to modulator therapy. [electronic resource]
Producer: 20201013Description: 606-613 p. digitalISSN:- 1873-5010
- Cells, Cultured
- Codon, Nonsense
- Cystic Fibrosis -- drug therapy
- Cystic Fibrosis Transmembrane Conductance Regulator -- genetics
- Gene Expression Profiling
- Homozygote
- Humans
- Membrane Transport Modulators -- pharmacology
- Mutation
- Nasal Mucosa -- metabolism
- Protein Stability -- drug effects
- RNA, Messenger -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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