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	1.	Developing PreDICT - a fully integrated data platform for preclinical in vivo data: learning from experience. [electronic resource] by Jones, Rhys D O Cooke, Marie Hinchliffe, James Morley, Justin Barry, Simon T Producer: 20180606 In: Drug discovery today vol. 22 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	2.	Improving the Accuracy of Predicted Human Pharmacokinetics: Lessons Learned from the AstraZeneca Drug Pipeline Over Two Decades. [electronic resource] by Davies, Michael Jones, Rhys D O Grime, Ken Jansson-Löfmark, Rasmus Fretland, Adrian J Winiwarter, Susanne Morgan, Paul McGinnity, Dermot F Producer: 20210505 In: Trends in pharmacological sciences vol. 41 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	3.	The Pharmacokinetic-Pharmacodynamic (PKPD) Relationships of AZD3229, a Novel and Selective Inhibitor of KIT, in a Range of Mouse Xenograft Models of GIST. [electronic resource] by Pilla Reddy, Venkatesh Anjum, Rana Grondine, Michael Smith, Aaron Bhavsar, Deepa Barry, Evan Guichard, Sylvie M Shao, Wenlin Kettle, Jason G Brown, Crystal Banks, Erica Jones, Rhys D O Producer: 20211102 In: Clinical cancer research : an official journal of the American Association for Cancer Research vol. 26 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	4.	Applications of Quantitative Systems Pharmacology in Model-Informed Drug Discovery: Perspective on Impact and Opportunities. [electronic resource] by Bradshaw, Erica L Spilker, Mary E Zang, Richard Bansal, Loveleena He, Handan Jones, Rhys D O Le, Kha Penney, Mark Schuck, Edgar Topp, Brian Tsai, Alice Xu, Christine Nijsen, Marjoleen J M A Chan, Jason R Producer: 20200819 In: CPT: pharmacometrics & systems pharmacology vol. 8 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	5.	Model-based drug discovery: implementation and impact. [electronic resource] by Visser, Sandra A G Aurell, Malin Jones, Rhys D O Schuck, Virna J A Egnell, Ann-Charlotte Peters, Sheila A Brynne, Lena Yates, James W T Jansson-Löfmark, Rasmus Tan, Beesan Cooke, Marie Barry, Simon T Hughes, Andrew Bredberg, Ulf Producer: 20140707 In: Drug discovery today vol. 18 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	6.	PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 4: prediction of plasma concentration-time profiles in human from in vivo preclinical data by using the Wajima approach. [electronic resource] by Vuppugalla, Ragini Marathe, Punit He, Handan Jones, Rhys D O Yates, James W T Jones, Hannah M Gibson, Christopher R Chien, Jenny Y Ring, Barbara J Adkison, Kimberly K Ku, M Sherry Fischer, Volker Dutta, Sandeep Sinha, Vikash K Björnsson, Thorir Lavé, Thierry Poulin, Patrick Producer: 20151008 In: Journal of pharmaceutical sciences vol. 100 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	7.	The MET Inhibitor AZD6094 (Savolitinib, HMPL-504) Induces Regression in Papillary Renal Cell Carcinoma Patient-Derived Xenograft Models. [electronic resource] by Schuller, Alwin G Barry, Evan R Jones, Rhys D O Henry, Ryan E Frigault, Melanie M Beran, Garry Linsenmayer, David Hattersley, Maureen Smith, Aaron Wilson, Joanne Cairo, Stefano Déas, Olivier Nicolle, Delphine Adam, Ammar Zinda, Michael Reimer, Corinne Fawell, Stephen E Clark, Edwin A D'Cruz, Celina M Producer: 20160519 In: Clinical cancer research : an official journal of the American Association for Cancer Research vol. 21 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	8.	PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: prediction of plasma concentration-time profiles in human by using the physiologically-based pharmacokinetic modeling approach. [electronic resource] by Poulin, Patrick Jones, Rhys D O Jones, Hannah M Gibson, Christopher R Rowland, Malcolm Chien, Jenny Y Ring, Barbara J Adkison, Kimberly K Ku, M Sherry He, Handan Vuppugalla, Ragini Marathe, Punit Fischer, Volker Dutta, Sandeep Sinha, Vikash K Björnsson, Thorir Lavé, Thierry Yates, James W T Producer: 20151008 In: Journal of pharmaceutical sciences vol. 100 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	9.	Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors. [electronic resource] by Kettle, Jason G Anjum, Rana Barry, Evan Bhavsar, Deepa Brown, Crystal Boyd, Scott Campbell, Andrew Goldberg, Kristin Grondine, Michael Guichard, Sylvie Hardy, Christopher J Hunt, Tom Jones, Rhys D O Li, Xiuwei Moleva, Olga Ogg, Derek Overman, Ross C Packer, Martin J Pearson, Stuart Schimpl, Marianne Shao, Wenlin Smith, Aaron Smith, James M Stead, Darren Stokes, Steve Tucker, Michael Ye, Yang Producer: 20191007 In: Journal of medicinal chemistry vol. 61 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	10.	Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer. [electronic resource] by Bradbury, Robert H Acton, David G Broadbent, Nicola L Brooks, A Nigel Carr, Gregory R Hatter, Glenn Hayter, Barry R Hill, Kathryn J Howe, Nicholas J Jones, Rhys D O Jude, David Lamont, Scott G Loddick, Sarah A McFarland, Heather L Parveen, Zaieda Rabow, Alfred A Sharma-Singh, Gorkhn Stratton, Natalie C Thomason, Andrew G Trueman, Dawn Walker, Graeme E Wells, Stuart L Wilson, Joanne Wood, J Matthew Producer: 20130930 In: Bioorganic & medicinal chemistry letters vol. 23 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	11.	AZD3514: a small molecule that modulates androgen receptor signaling and function in vitro and in vivo. [electronic resource] by Loddick, Sarah A Ross, Sarah J Thomason, Andrew G Robinson, David M Walker, Graeme E Dunkley, Tom P J Brave, Sandra R Broadbent, Nicola Stratton, Natalie C Trueman, Dawn Mouchet, Elizabeth Shaheen, Fadhel S Jacobs, Vivien N Cumberbatch, Marie Wilson, Joanne Jones, Rhys D O Bradbury, Robert H Rabow, Alfred Gaughan, Luke Womack, Chris Barry, Simon T Robson, Craig N Critchlow, Susan E Wedge, Stephen R Brooks, A Nigel Producer: 20140401 In: Molecular cancer therapeutics vol. 12 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)