MHC class II molecules play a role in the selection of autoreactive class I-restricted CD8 T cells that are essential contributors to type 1 diabetes development in nonobese diabetic mice. [electronic resource]
Producer: 20040420Description: 871-9 p. digitalISSN:- 0022-1767
- Animals
- Antigen-Presenting Cells -- cytology
- Autoantigens -- immunology
- CD8-Positive T-Lymphocytes -- immunology
- Cell Differentiation -- genetics
- Clonal Anergy -- genetics
- Diabetes Mellitus, Type 1 -- genetics
- Down-Regulation -- genetics
- Female
- Genetic Carrier Screening
- Genetic Variation -- immunology
- H-2 Antigens -- genetics
- Haplotypes
- Hematopoietic Stem Cells -- cytology
- Histocompatibility Antigens Class II -- biosynthesis
- Histocompatibility Testing
- Lymphocyte Activation -- genetics
- Male
- Mice
- Mice, Inbred NOD
- Mice, Transgenic
- Receptors, Antigen, T-Cell -- biosynthesis
- Signal Transduction -- genetics
- T-Lymphocyte Subsets -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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