Integrative genetic analysis of mouse and human AML identifies cooperating disease alleles. [electronic resource]
Producer: 20160513Description: 25-34 p. digitalISSN:- 1540-9538
- Alleles
- Animals
- Cell Transformation, Neoplastic -- genetics
- Chromosomes, Human, Pair 21
- Chromosomes, Human, Pair 8
- Core Binding Factor Alpha 2 Subunit -- genetics
- Disease Models, Animal
- Epistasis, Genetic
- Gene Expression Regulation, Leukemic
- Gene Knockout Techniques
- Genomics -- methods
- Humans
- Leukemia, Myeloid, Acute -- genetics
- Mice
- Mutation
- Oncogene Proteins, Fusion -- genetics
- Phenotype
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 -- genetics
- RUNX1 Translocation Partner 1 Protein
- Translocation, Genetic
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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