Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines. [electronic resource]
Producer: 20190903ISSN:- 2218-273X
- Antineoplastic Agents -- chemistry
- Apoptosis -- drug effects
- Ascomycota -- chemistry
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Humans
- Macrolides -- chemistry
- Membrane Potential, Mitochondrial -- drug effects
- Molecular Structure
- Proto-Oncogene Proteins c-akt
- Reactive Oxygen Species -- analysis
- Secondary Metabolism
- Structure-Activity Relationship
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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