Atorvastatin enhances neurite outgrowth in cortical neurons in vitro via up-regulating the Akt/mTOR and Akt/GSK-3β signaling pathways. [electronic resource]
Producer: 20121030Description: 861-72 p. digitalISSN:- 1745-7254
- Animals
- Atorvastatin
- Cells, Cultured
- Cerebral Cortex -- cytology
- Enzyme Activation -- drug effects
- Glycogen Synthase Kinase 3 -- metabolism
- Glycogen Synthase Kinase 3 beta
- Heptanoic Acids -- pharmacology
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Neurites -- drug effects
- Neurons -- cytology
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Pyrroles -- pharmacology
- Rats
- Rats, Sprague-Dawley
- Signal Transduction -- drug effects
- TOR Serine-Threonine Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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