Characterization of a novel function-blocking antibody targeted against the platelet P2Y1 receptor. [electronic resource]
Producer: 20160412Description: 637-44 p. digitalISSN:- 1524-4636
- Animals
- Antibodies -- metabolism
- Binding Sites
- Binding, Competitive
- Blood Platelets -- drug effects
- Carotid Artery Injuries -- blood
- Deoxyadenine Nucleotides -- metabolism
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Epitopes
- Fibrinolytic Agents -- metabolism
- Hemorrhage -- chemically induced
- Hemostasis -- drug effects
- Humans
- Ligands
- Mice, Inbred C57BL
- Mice, Knockout
- Phosphatidylserines -- blood
- Platelet Activation -- drug effects
- Platelet Aggregation -- drug effects
- Platelet Aggregation Inhibitors -- metabolism
- Platelet Glycoprotein GPIIb-IIIa Complex -- antagonists & inhibitors
- Purinergic P2Y Receptor Antagonists -- metabolism
- Receptors, Purinergic P2Y1 -- blood
- Secretory Vesicles -- drug effects
- Thrombosis -- blood
- Time Factors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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