Intratumoral CD40 activation and checkpoint blockade induces T cell-mediated eradication of melanoma in the brain. [electronic resource]
Producer: 20180911Description: 1447 p. digitalISSN:- 2041-1723
- Adenoviridae -- genetics
- Animals
- Brain -- pathology
- Brain Neoplasms -- immunology
- CD4-CD8 Ratio
- CD40 Antigens -- agonists
- CD40 Ligand -- genetics
- CD8-Positive T-Lymphocytes -- immunology
- CTLA-4 Antigen -- antagonists & inhibitors
- Cell Line, Tumor
- Enzyme Activation
- Female
- Immunotherapy -- methods
- Melanoma, Experimental -- immunology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Programmed Cell Death 1 Receptor -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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