Accurate classification of BRCA1 variants with saturation genome editing. [electronic resource]
Producer: 20190509Description: 217-222 p. digitalISSN:- 1476-4687
- BRCA1 Protein -- genetics
- Cell Line
- Exons -- genetics
- Female
- Gene Editing
- Genes, Essential -- genetics
- Genetic Predisposition to Disease -- classification
- Genetic Variation -- genetics
- Genome, Human -- genetics
- Hereditary Breast and Ovarian Cancer Syndrome -- genetics
- Humans
- Loss of Function Mutation -- genetics
- Models, Molecular
- Prognosis
- RNA, Messenger -- genetics
- Recombinational DNA Repair -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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