Synthesis, resolution, and biological evaluation of atropisomeric (aR)- and (aS)-16-methyllamellarins N: unique effects of the axial chirality on the selectivity of protein kinases inhibition. [electronic resource]
Producer: 20131126Description: 7289-301 p. digitalISSN:- 1520-4804
- Antineoplastic Agents -- chemical synthesis
- Cell Line, Tumor
- Chemistry Techniques, Synthetic
- DNA Topoisomerases, Type I -- chemistry
- Humans
- Molecular Docking Simulation
- Polycyclic Compounds -- chemical synthesis
- Protein Conformation
- Protein Kinase Inhibitors -- chemical synthesis
- Protein Kinases -- chemistry
- Stereoisomerism
- Structure-Activity Relationship
- Substrate Specificity
- Topoisomerase I Inhibitors -- chemical synthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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