Nuclear 82-kDa choline acetyltransferase decreases amyloidogenic APP metabolism in neurons from APP/PS1 transgenic mice. [electronic resource]
Producer: 20150312Description: 32-42 p. digitalISSN:- 1095-953X
- Adaptor Proteins, Vesicular Transport -- genetics
- Amyloid Precursor Protein Secretases -- metabolism
- Amyloid beta-Peptides -- metabolism
- Amyloid beta-Protein Precursor -- genetics
- Animals
- Aspartic Acid Endopeptidases -- metabolism
- Brain -- metabolism
- Cell Line, Tumor
- Cell Nucleus -- metabolism
- Cells, Cultured
- Choline O-Acetyltransferase -- metabolism
- Cholinergic Neurons -- metabolism
- Gene Expression
- HEK293 Cells
- Humans
- Mice, Transgenic
- Microarray Analysis
- Neurons -- metabolism
- Peptide Fragments -- metabolism
- Presenilin-1 -- genetics
- Promoter Regions, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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