Inhibition of autophagy enhances DENSpm-induced apoptosis in human colon cancer cells in a p53 independent manner. [electronic resource]
Producer: 20181003Description: 297-317 p. digitalISSN:- 2211-3436
- Adenine -- analogs & derivatives
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Autophagy -- drug effects
- Beclin-1 -- antagonists & inhibitors
- Caspase 3 -- metabolism
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Cell Survival -- drug effects
- Colonic Neoplasms -- drug therapy
- HCT116 Cells
- HT29 Cells
- Humans
- Membrane Potential, Mitochondrial -- drug effects
- Polyamines -- metabolism
- RNA, Small Interfering -- pharmacology
- Spermine -- analogs & derivatives
- Tumor Suppressor Protein p53 -- physiology
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Publication Type: Journal Article
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