Methylpyrrole inhibitors of BET bromodomains. [electronic resource]
Producer: 20170905Description: 2225-2233 p. digitalISSN:- 1464-3405
- Animals
- Antineoplastic Agents -- chemical synthesis
- Binding Sites
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Crystallography, X-Ray
- Drug Design
- Half-Life
- Humans
- Mice
- Molecular Dynamics Simulation
- Multiple Myeloma -- drug therapy
- Nuclear Proteins -- antagonists & inhibitors
- Pyrroles -- chemical synthesis
- Structure-Activity Relationship
- Transcription Factors -- antagonists & inhibitors
- Transplantation, Heterologous
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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