Mutation of the salt bridge-forming residues in the ETV6-SAM domain interface blocks ETV6-NTRK3-induced cellular transformation. [electronic resource]
Producer: 20131224Description: 27940-50 p. digitalISSN:- 1083-351X
- Animals
- Calorimetry
- Cell Transformation, Neoplastic
- Humans
- Lysine -- chemistry
- Magnetic Resonance Spectroscopy
- Mice
- Mice, Nude
- Mutation
- NIH 3T3 Cells
- Polymers -- chemistry
- Protein Structure, Tertiary
- Proto-Oncogene Proteins c-ets -- chemistry
- Receptor, trkC -- chemistry
- Repressor Proteins -- chemistry
- Salts -- chemistry
- Signal Transduction
- Static Electricity
- Tyrosine -- chemistry
- ETS Translocation Variant 6 Protein
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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