Chronic treatment with cisplatin induces chemoresistance through the TIP60-mediated Fanconi anemia and homologous recombination repair pathways. [electronic resource]
Producer: 20181231Description: 3879 p. digitalISSN:- 2045-2322
- Acetylation
- BRCA1 Protein -- genetics
- Biomarkers
- Cell Cycle -- drug effects
- Cell Line
- Cisplatin -- pharmacology
- DNA Breaks, Double-Stranded -- drug effects
- Drug Resistance -- genetics
- Fanconi Anemia -- drug therapy
- Fanconi Anemia Complementation Group D2 Protein -- genetics
- Gene Expression Regulation -- drug effects
- Histones -- metabolism
- Homologous Recombination
- Humans
- Lysine Acetyltransferase 5 -- genetics
- Promoter Regions, Genetic
- Protein Binding
- RNA Interference
- RNA, Small Interfering -- genetics
- Recombinational DNA Repair
- Signal Transduction
- Sister Chromatid Exchange
- Transcription Initiation Site
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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